Some may be a better fit for you than others. Your healthcare provider will watch you closely for 30 minutes after each dose. Venofer is for use in adults and children at least 2 years old. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Understanding what thoseside effectsare can lead to a strategy to prevent them. This survey is being conducted by the WebMD marketing sciences department. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. People in the study received treatment with either Injectafer or Venofer. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. Venofer may cause significant hypotension (decreased blood pressure). Iron infusion benefits. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. If you have questions about using Injectafer in a child, talk with your doctor. In the US - Call your doctor for medical advice about side effects. For example: Say you weigh 105 pounds (about 48 kilograms). Its caused by your body not having enough iron, which is needed to make hemoglobin. And this can lead to anemia, including IDA. Keep in mind that the risk of certain pregnancy-related problems can be increased if iron deficiency anemia (IDA) is left untreated. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). * This is a partial list of mild side effects from Injectafer. Keep out of reach of children. If either is present, do not use the liquid. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. Call your doctor for medical advice about side effects. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. weakness. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. A lack of iron can lead to iron deficiency anaemia if left untreated. With IDA, you have low hemoglobin levels. How is Venofer (iron sucrose) given? Together, you and your doctor can discuss the benefits and risks of treatment options for anemia. Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. dizziness. I used to get a different type but my . If youre concerned about weight changes while youre taking Injectafer, talk with your doctor. upper respiratory infection. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. Venofer Side Effects. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. This may lead to the person needing a higher dose compared to someone who is muchsmaller. Keep all medications away from children and pets. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. muscle pain. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. Feraheme also comes as a liquid thats given by IV infusion. US residents can call their local poison control center at 1-800-222-1222. People with IDA have low blood levels of hemoglobin. What is Venofer? They can give you tips on how to deal with any side effects that may be bothersome. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. However, be sure to take the dosage your doctor prescribes for you. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. Learn about uses, cost, how it works, and more. These side effects may include constipation and diarrhea. Low iron saturation, or iron deficiency, has various possible causes. Brandon ColbyMD, a medical expert specializing in preventive medicine and clinicalgenomics. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. Vomiting. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. These side effects can range from being mild to severe. These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. These are not all of the side effects that may occur. Call your doctor for instructions if you miss an appointment for your Venofer injection. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. Pain in your limbs. Injectafer helps to treat IDA by providing an iron infusion directly into your body. With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. There are 2 tests that your doctor will likely I hope you found answers and are feeling better now. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Theyll recommend how to manage your condition. If that happens, and your doctor thinks Injectafer is a good treatment option for you, you can receive another treatment course of the drug. They can recommend appropriate treatment options. Many patients with kidney disease cannot get enough iron from food and require injections. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. Its possible to get rid of or reduce the severity ofside effects. Most people will metabolize medication by half every time it circulates the body. Keep all regular medical and laboratory appointments. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You may also report side effects at https://www.fda.gov/medwatch. Injectafer is available only as a brand-name medication. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. Severeside effectsmay end up causing a lot of disruption in a persons life. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. (See also Notes section.). The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. generalized weakness. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and VenAccess is a trademark of Vifor (International) Inc. Switzerland. This test measures the amount of hemoglobin in your blood. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Does Venofer Vial interact with other medications? Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. Injectafer infusions are given over a period of at least 15 minutes. Pain, swelling, or redness at the injection site may occur. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. But even if youre not at risk for the condition, your doctor may still monitor your phosphorus levels. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. Source: Wolters Kluwer Health. Injectafer should be stored between 68F to 77F (20C to 25C). Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. other treatments you receive, you will need to go back for several treatments with Venofer. In the first group, some people continued taking iron by mouth, while other people took Injectafer. So theres no recommended pediatric dosage for Injectafer. Venofer® (iron sucrose injection, USP) is available by prescription only. Back pain. Any long-term side effects/dangers from iron infusions? 2023 Medicine.com All rights reserved. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. <> Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. * Sex and gender exist on spectrums. (And Injectafer is used to treat IDA.) Renal elimination is negligible. Side effectsare uncomfortable reactions to medications or drugs. This includes your doctors, nurses, pharmacists, and dentists. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. But you likely wont feel the drug working inside of you. You will need frequent medical tests to help your doctor determine how long to treat you with Venofer. Also tell them about any vitamins, herbs, and supplements you use. A healthcare provider will give you this injection. These people may lose weight as their anemia improves because theyre more active. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. It can be given as a slow injection over 2 to 5 minutes or as an infusion. FG Trade/E+ sia Getty Images Change in taste. Iron infusion side effects vary depending on which form is being used. 5 0 obj (A class of medications describes a group of drugs that work in the same way.). This document does not contain all possible drug interactions. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. And theyll recommend how soon after starting the drug you need to have this level checked. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Injectafer isnt a medication that youll take regularly on a schedule. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. I can't take oral supplements because they cause horrible debilitating Constipation. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. 3 0 obj The following information describes dosages that are commonly used or recommended. This can be very helpful in . Consult your pharmacist or local waste disposal company. If your symptoms or health problems do not get better or if they become worse, call your doctor. Here we look at how Injectafer and Venofer are alike and different. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. It is given into a vein for a period of time. As a result, you may not make as much EPO as usual. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. When the toxins are released into the air, they can be inhaled and cause irritation to the lungs. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. 2 0 obj Pain, swelling, or redness at the injection site may occur. For more information about Injectafers approved uses, see the section Injectafer uses below. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. And babies born to those who took Injectafer during pregnancy didnt have any major congenital anomalies (also sometimes called birth defects). A variety of tests can diagnose iron deficiency anemia. The benefit of treating your condition during pregnancy may outweigh any risks. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. WebMD provides common contraindications for Venofer Vial. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Consult the product instructions and your pharmacist for storage details. Its because everyones body is different. Innovators Monograph For instance, someone with lowblood pressuremay receive a medication to prevent migraines that lowersblood pressure, this may causeseriousside effects. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Tell your doctor if you are taking iron supplements or other iron-based oral medications. The infusion will take between 15-30 minutes if it is given in. The information provided is not intended to replace your healthcare provider's medical advice. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. HRT, like other medications, does have some side effects and these are thought to be quite common. There are different types of anemia, but IDA is the most common type. After the infusion, you can drive yourself home and return to your usual activities. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). The following information is provided for clinicians and other healthcare professionals. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. Learn more about the types of tests and treatment. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. fever. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. Review our medical disclaimer. The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. Injectafer contains the active drug ferric carboxymaltose. Theseside effectsmay last as long as they are undercancer treatment. Venofer injection contains iron sucrose, a form of the mineral iron. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. Together, you and your doctor can develop a treatment plan thats best for you. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. This information should not be used to decide whether or not to take Venofer or any other medicine. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. But for other people, doing so could lead to having too much iron in their body. Injectafer begins working as soon as it enters your body. Find comprehensive medical information for Venofer intravenous on RxList including its uses, side effects, precautions, drug interactions, overdose, pill images & warnings . For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Answer by DrLact: About Venofer usage in lactation. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. Heres some detail on certain side effects this drug may cause. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. We cancelled my 5th because of the reaction. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Does Venofer Vial interact with other drugs you are taking? Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. Do not exceed 1,500 mg of iron per dosing course. Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. (One treatment course includes two doses of the drug.) Throw away unused or expired drugs. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. % . Health careproviderscan provide information on how longside effectslast by checking amedication guide. Serious side effects should be reported to a physician and/or PharmD for medical advice. I had Venofer infusions, 2 rounds now in the span of three years. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Brand-name medications usually cost more than generics. Other drugs are available that can treat iron deficiency anemia (IDA). Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. endobj endobj 12 Medicines That Could Help, List Venofer Vial side effects by likelihood and severity. One of the most commonly used tests to monitor IDA is the hemoglobin test. Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. Sharing this information can help you avoid potential interactions. These are not all the side effects that may occur; contact your healthcare provider if you have questions. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. administered at your doctors office or an infusion center. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. Nausea. MNT is the registered trade mark of Healthline Media. Injectafer contains the active drug ferric carboxymaltose. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Together, they can recommend ways to help you manage a body weight thats healthy for you. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. Most of these side effects may go away within a few days or a couple of weeks. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. Injectafer and Venofer are both brand-name drugs. Brand-name medications usually cost more than generics. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Details. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. Injectafer is approved to treat iron deficiency anemia (IDA). A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. The oral form of the drug, called sucroferric oxyhydroxide and used . With IDA, you have anemia (low red blood cell level) thats due to not having enough iron in your body. All of the people took iron by mouth for 2 weeks. Heart failure: Could a low sodium diet sometimes do more harm than good? In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. This way, if you have an allergic reaction to Injectafer, your healthcare professional can treat your reaction.